Yes they can. Don't know if you will make 1/2 sec but you will gain for sure.
On my MYP with the uberturbine (Pirelli zero elect) the 0-62 mph is 0.3 sec slower than when on my forged 20" wheels(Hankook ion EVO) with 255 instate of 255/275 stock on the 21" uberturbines