Your 22” wheels reduces range 10%.
Check your tires pressures. Should be at least 42psi cold. If you were using AC at lot it can reduce range another 5%. Hills/mountains are also big range reducers. On my MX 100D we usually can only get 245 miles of actual range with 4 adults in the car and driving 75mph.
What was your trip wh/mi?
22s will actually cost you 20%+ range loss (Tesla Model S and Model X: Here’s how wheel size can affect efficiency). In my tests of our 100D Model X with 20s vs. 22s I see almost exactly 22% loss of range with the 22s correcting for temperature.
This will lead to actual range of about 225 miles of range in a P100D ideally with 22s. Not sure what would cause an additional 25%+ range loss if temperatures were not cold.
In similar driving conditions my P100D Model S averages about 350 Whr/mile with 21s. If we use standard difference you should be using about 405 Whr/mile and get a range of about 247 miles.
So there is something amiss here if you are getting a range of 161 miles give or take.