I was providing feedback to Tesla last year with a nasty bug they had in the firmware causing a buffer overflow type error with the Radar unit, which basically crashed part of the canbus. While chatting with the techs on the issue looking for workarounds in case it happened while I was on the motorway, They stated that the two button reset was now very basic in operation and it no longer actually shut down the hardware, just did a very soft reboot. Apparently it was actually causing more issues than it fixed before as it hard shut down and could cause corruption, so they dumbed it right down (probably why you don't hear people talking much about holding the brake down while resetting). Just leaving the car to sleep with sentry off and walking away was the only way to actually reboot the system properly. Two button reset was only for clearing some immediate software crashes, and if you'd already left the car to sleep wouldn't make any difference. In my case you couldn't clear the radar issue with the two button reset and you really did just need to walk away from the car for half an hour.
No harm in trying it but if the above is true it wouldn't fix anything that having left the car to sleep wouldn't have already fixed.